Scientific excellenceScientific excellence
Rigorous, research-driven innovation built on 20+ years of genetic code expansion expertise.
Rigorous, research-driven innovation built on 20+ years of genetic code expansion expertise.
Rewriting Proteins to Reverse NeurodegenerationRewriting Proteins to Reverse Neurodegeneration
Tiragena combines genetic code expansion, precision protein design, and translational delivery science to build durable therapies for neurodegeneration and age-related decline.
Tiragena combines genetic code expansion, precision protein design, and translational delivery science to build durable therapies for neurodegeneration and age-related decline.
Genetic Code Expansion TechnologyGenetic Code Expansion Technology
Nature's genetic code uses 20 standard amino acids to build all proteins. Tiragena's proprietary technology expands this code, enabling us to incorporate non-canonical amino acids (ncAAs) with novel properties—creating therapeutic proteins impossible to achieve in nature.
Nature's genetic code uses 20 standard amino acids to build all proteins. Tiragena's proprietary technology expands this code, enabling us to incorporate non-canonical amino acids (ncAAs) with novel properties—creating therapeutic proteins impossible to achieve in nature.
Read the full science overviewRead the full science overviewWhat defines our workWhat defines our work
Three principles guide every program, partnership, and therapeutic decision we make.
Three principles guide every program, partnership, and therapeutic decision we make.
Patient focusPatient focus
Every decision guided by meaningful impact for patients and families affected by devastating diseases.
Every decision guided by meaningful impact for patients and families affected by devastating diseases.
Safety firstSafety first
Transient, reversible therapies engineered to prioritize patient safety at every stage.
Transient, reversible therapies engineered to prioritize patient safety at every stage.
What can Tiragena do for you?What can Tiragena do for you?
Science & platform
Genetic code expansion and orthogonal translation for neurodegenerative disease biology.
Learn moreTherapeutic pipeline
Our portfolio spans engineered research proteins, next-generation ADCs, and in vivo protein editing programs aimed at diseases of aging and neurodegeneration.
View pipelinePublications
Peer-reviewed genetic code expansion and protein engineering research.
Browse publicationsPatients
Resources for patients and families navigating neurodegenerative disease.
Patient informationPartners & investors
We collaborate with academic centers, clinical partners, and industry to accelerate translation. If you are interested in collaboration, reach out through our contact page.
PartnersCareers
We are building a multidisciplinary team passionate about protein engineering, translational science, and patient impact.
CareersNews & insightsNews & insights
Cold-adapted orthogonal translation systems
How flexible psychrophilic scaffolds improve non-canonical amino acid incorporation performance.
Critical assessment of genetic code expansion
Foundational analysis of efficiency limits and design directions for translational biotech.
Browse the full publications catalog
Filterable archive of peer-reviewed GCE and protein engineering outputs.
ConnectConnect
ContactContact
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- General, investor, partnership, and media inquiries: info@tiragena.com
- Scientific and technical inquiries: science@tiragena.com
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